Congratulations to Candice for her excellent work on genetic modification of differentiating iPSCs to render resultant Hepatocyte-Like Cells traceable by non-invasive whole-body in vivo imaging. We are very proud of Candice, and invite you to enjoy reading about this exciting research here!

Graphical abstract


• iPSC-derived hepatocyte-like cells (HLCs) rendered traceable in vivo.
• Reproducible lentivirus-based gene transfer during the differentiation process.
• Protocol and reporter expression did not negatively impact on HLC maturation.
• Proof-of-principle shown for whole-body SPECT/CT-afforded HLC in vivo tracking.