We explain how in vivo imaging can aid the development of molecular and cell-based anti-cancer immunotherapies. We describe the principles of imaging host T-cells and adoptively transferred therapeutic T-cells as well as the value of traceable cancer cell models in immunotherapy development. Our emphasis is on in vivo cell tracking methodology, including important aspects and caveats specific to immunotherapies.
Congratulations to successfully completing your PhD !!!
Winston Churchill Fellowships are awarded to research the world’s best ideas, innovations and practices within the field of science and science education. Madeleine will be exploring environmentally sustainable laboratory practices, in the USA and share her findings with scientists and policymakers in the UK.
Many Congratulations to Madeleine!
“My goal is to drastically reduce the volume of non-essential waste sent for incineration, by introducing changes to education, policy and incentivisation. I strongly believe that we need to empower frontline scientists to make positive changes in their own workplaces. I will shape my learnings from the US, and subsequent discussions in the UK, into a series of practical recommendations that can be adopted by scientists. By collaborating directly with researchers and policymakers, we can show that high-quality research and sustainable lab practices are not mutually exclusive.” – Madeleine Iafrate
Then please have a look at our latest Open Access Review in Clinical and Translational Medicine: (doi.org/10.1186/s40169-020-0268-z). Congratulations to Candice for a well-received comprehensive and very timely review article!
What an exciting day at the end of 2019!
After years of hard work, Rainbow finally obtained the first in vivo imaging data of her new DNA imaging compound!
And Rico, our newest team member, joined in gaining valuable insight into the routine of radionuclide in vivo imaging.
…who received the 2019 MRes in Translational Cancer Medicine Course Award at King’s College London recognizing his outstanding performance.
Congratulations to Candice for her excellent work on genetic modification of differentiating iPSCs to render resultant Hepatocyte-Like Cells traceable by non-invasive whole-body in vivo imaging. We are very proud of Candice, and invite you to enjoy reading about this exciting research here!
• iPSC-derived hepatocyte-like cells (HLCs) rendered traceable in vivo.
• Reproducible lentivirus-based gene transfer during the differentiation process.
• Protocol and reporter expression did not negatively impact on HLC maturation.
• Proof-of-principle shown for whole-body SPECT/CT-afforded HLC in vivo tracking.
Great talk, lots of people in the audience and great questions from the audience, too – a very successful day for Candice!
Congratulations to Candice and many thanks for the honour to be showcased among the top scientific abstracts at the World Molecular Imaging Conference 2019!
…the Best Poster Presentation Prize at the RSC Radiochemistry Group’s Young Researchers’ Meeting 2019.